Autophagy is a degradation pathway

2019-08-15

Autophagy is a degradation pathway existing in all eukaryotic organisms. It is the main system for the degradation of bulk cytoplasmic components in cells (Feng et al., 2014), but it also plays a crucial role in other processes, as immunity (Wileman, 2013), mitochondrial (Dengjel and Abeliovich, 2014) and peroxisomal (Till et al., 2012) degradation and clearance of misfolded protein PPACKII (Lamark and Johansen, 2012).

Inhibition of DHODH is reflected by

2019-08-14

Inhibition of DHODH is reflected by an antiproliferative effect on peripheral blood mononuclear Enfuvirtide (PBMCs), which can be measured by the inhibitory effect on their phytohemagglutinin (PHA) stimulated growth.

In humans several different small

2019-08-13

In humans, several different small ubiquitin-related modifier (SUMO) paralogs can be conjugated to cellular proteins.

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2018-07-29