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liothyronine sodium br STAR Methods br Acknowledgments
2021-08-13
STAR★Methods Acknowledgments We thank the City of Hope core facilities, including the Animal Model Core, Bioinformatic Core, NMR Core, Flow Cytometry Core, and Florescence Microscopy Core for excellent technical support, and NIH grants R01GM086171, R01GM102538, and R01CA212119, R01CA216987, an
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The thermal behavior of the UV sensitive nanocomposites
2021-08-13
The thermal behavior of the UV-sensitive nanocomposites was investigated by DSC before and after irradiation in an extended temperature range (from −40 to 250 °C). Fig. 4a shows the thermograms of the non-irradiated GNP-DNA/PDMS nanocomposites in comparison with a neat PDMS sample. The filler-loaded
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br Introduction Acylglycerol acyltransferases AGATs are
2021-08-13
Introduction Acylglycerol acyltransferases (AGATs) are predominantly responsible for triglyceride synthesis in the body, via two major pathways: the glycerol phosphate (GP) pathway (Kennedy, 1957) and the monoacylglycerol (MG) pathway (see Coleman and Lee, 2004, Yen et al., 2008). The final step
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Soybean Glycine max is an important
2021-08-13
Soybean (Glycine max) is an important oilseed and can be a useful source of epoxy fatty acids (EFAs). This UFA contains an oxygen bridge across adjacent carbon atoms at single or multiple positions in the acyl chain, making them highly reactive and prone to cross-linking, and thus valuable industria
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Are the hydrogens removed simultaneously or
2021-08-13
Are the hydrogens removed simultaneously or one by one? — Δ1-KSTDs can catalyze the exchange of alkali-labile tritium or deuterium atoms at the C2 Reutericyclin of their substrates, even when enzyme turnover was prevented by the absence of an electron acceptor for the oxidative half-reaction [97,98]
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Parathyroid hormone (1-34) (human) In order to assess quanti
2021-08-13
In order to assess quantitatively the contribution of the ung, dug and dut Parathyroid hormone (1-34) (human) to uracil-DNA accumulation in E. coli, we have developed a novel method for measuring uracil residues in DNA that is based on the approach of Kow and co-workers [33] for measuring AP-sites
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br Material and methods br Results br Discussion In the
2021-08-13
Material and methods Results Discussion In the present study, twenty strains of Y. enterocolitica were analyzed for their inhibitory potential on cysteine proteases. Five of these strains belonged to bioserotype 4/O:3, which is distinguished for its pathogenicity towards humans. The rest of
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Elevated production of cysLTs in asthma and rhinitis in
2021-08-13
Elevated production of cysLTs in pdgfr inhibitor and rhinitis in general and aspirin-sensitive disease in particular10, 11, 26, 27 has been implicated in causing epithelial cell activation and excessive mucus secretion, which characterize these diseases.2, 28 It is of particular interest, therefore
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CysLTs trigger contractile and inflammatory processes throug
2021-08-13
CysLTs trigger contractile and inflammatory processes through the specific interaction with cell surface receptors belonging to the rhodopsin family of the G protein-coupled receptor (GPCR) genes. Until now, two receptor subtypes have been cloned, namely CysLT1 and CysLT2[8]. In particular, when the
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Because flavonoids are widely considered to contribute
2021-08-13
Because flavonoids are widely considered to contribute to health benefits in humans, including anti-inflammatory, antibacterial, antiviral, anticancer, antiplatelet properties, and free radical scavenging capacity (Xiao et al., 2011), efforts have frequently been made to increase their bioavailabili
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br Results and discussion br Conclusion br Experimental
2021-08-13
Results and discussion Conclusion Experimental section Pharmacological studies Introduction Survival analysis is a set of statistical methods that aim at modeling the relationship between a set of predictor variables and an outcome variable and, in particular, prediction of the time w
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Many PIM inhibitors have been reported to
2021-08-13
Many PIM inhibitors have been reported to date [7], [8], [9] however, none of them has been marketed so far. SGI-1776 is a representative first-generation PIM inhibitor, which had been under clinical trials for leukemia and prostate cancer [10]. While most of the first-generation PIM inhibitors are
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Nociceptive and hyperalgesic actions of ET are produced thro
2021-08-13
Nociceptive and hyperalgesic actions of ET-1 are produced through ETA and ETB receptors. Previous reports indicate that ETA receptor antagonists in peripheral tissues are effective in inhibiting ET-1 induced hyperalgesia, and attenuation of neuropathic pain in rats [16]. Studies have also shown that
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Previously we have shown that
2021-08-13
Previously, we have shown that the overexpression of ERRγ induces exercise-like oxidative muscle remodeling without engaging changes in the expression level or activity of PGC1α (Narkar et al., 2011). In this study, overexpression of ERRγ in PKO muscle reveals that ERRγ-activated target genes can ac
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br Materials and methods br Results and discussion br
2021-08-12
Materials and methods Results and discussion Conclusions Acknowledgements This work was supported financially by the LIAONING S&T Project (No. 20180550107) and Basic Scientific Research Funds of DLNU (0918110143). Introduction Since 1970s, numerous artificial mimetic enzymes have bee
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