• The relatively high concentration of HT used in this study

  2023-03-28

  

  The relatively high concentration of 5-HT used in this study (100 µM) is consistent with the concentrations used in other published ex vivo studies (Ropert and Guy, 1991, Passani et al., 1994, Shen and Andrade, 1998). In our paradigm 5-HT was focally applied at the surface of the slice via a fast pe

• Introduction br This paper is a commentary

  2023-03-28

  

  Introduction This paper is a commentary on the history of language among the Aché. What was language for the Aché prior to contact with Paraguayan society? How has the Aché language come to be endangered? Why is language such an important issue today? In exploring these questions I come to a slig

• Finasteride was the first steroidal reductase inhibitor appr

  2023-03-27

  

  Finasteride (13) was the first steroidal 5α-reductase inhibitor approved by the US Food and Drug Administration (FDA) in 1992 for treatment of BPH. In fact, long term clinical studies with this drug demonstrated a sustained reduction of the prostatic specific antigen and an overall improvement in BH

• Cancer cells manifest characteristic abnormal growth propert

  2023-03-27

  

  Cancer Cy5 amine (non-sulfonated) manifest characteristic abnormal growth properties accompanying clonal evolution of cells displaying progressively increasing genomic instability capable of invasion and metastasis to distant organ sites. With the emerging knowledge about the role of known oncogene

• Cancer cells manifest characteristic abnormal growth propert

  2023-03-27

  

  Cancer Cy5 amine (non-sulfonated) manifest characteristic abnormal growth properties accompanying clonal evolution of cells displaying progressively increasing genomic instability capable of invasion and metastasis to distant organ sites. With the emerging knowledge about the role of known oncogene

• PGR regulation of epithelium stroma crosstalk is proven by

  2023-03-27

  

  PGR regulation of epithelium–stroma crosstalk is proven by numerous studies that utilize genetically engineered mouse models. Before embryo implantation, epithelial PGR mediates the progesterone signal to transcriptionally increase the Ihh levels 13, 15. Epithelial IHH then activates the stromal hed

• To our knowledge this study collected all published research

  2023-03-24

  

  To our knowledge, this study collected all published research of occurrence of iMDK in water, sediment and aquatic organisms of typical Lakes by 2017 according to http://www.cnki.net/, https://xue.glgoo.net/, http://xueshu.baidu.com/, and http://www.sciencedirect.com/. Some information of Lakes are

• To our knowledge this study collected all published research

  2023-03-24

  

  To our knowledge, this study collected all published research of occurrence of iMDK in water, sediment and aquatic organisms of typical Lakes by 2017 according to http://www.cnki.net/, https://xue.glgoo.net/, http://xueshu.baidu.com/, and http://www.sciencedirect.com/. Some information of Lakes are

• br Androgen interference with the action of arachidonic

  2023-03-23

  

  Androgen interference with the action of arachidonic TMC647055 Choline salt metabolites’ actions; the other side of the coin Arachidonic acid, being a polyunsaturated fatty acid present in the phospholipids of the membrane of cells, is highly abundant within the organism. It is mainly involved i

• Immunohistochemistry in tissue samples showed

  2023-03-23

  

  Immunohistochemistry in tissue samples showed the expression of several nuclear receptor co-activators, including NCOA1, NCOA2, NCOA3, CREBBP, and EP300, in 85–100% of Methotrexate tumors even some of which lacked AR expression (Boorjian et al., 2009). Knockdown of each co-activator also resulted i

• tachykinin receptor We found evidence of the interaction bet

  2023-03-22

  

  We found evidence of the interaction between AR and hemiacetals by evaluating the effect of glucose on l-idose reduction. l-idose was recently proposed as the best AR substrate able to mimic glucose [38]. This aldose is structurally very closely related to d-glucose, from which it differs only in th

• In summary the different types of interstitial cells found

  2023-03-22

  

  In summary, the different types of interstitial cells found in the current study are illustrated in Fig. 7A (see legend for further details), which is suggestive of a heterogeneous complex network of interstitial cells communicating with each other. The possible signaling pathways involving this int

• In pioneering work from Ikeda and colleagues showed that

  2023-03-22

  

  In 2006, pioneering work from Ikeda and colleagues showed that GMF localizes to and regulates the AMD-070 hydrochloride cytoskeleton (see Glossary), and noted its sequence similarity to ADF/cofilin[11]. In 2009, the structure of GMF [6] was solved, revealing it to be a bona fide member of the actin

• br Dual role of autophagy in human

  2023-03-22

  

  Dual role of autophagy in human diseases Emerging evidence suggests that autophagy serves as a double-edged sword in several human diseases, such as CNS diseases (Rubinsztein et al., 2015), arteriosclerosis (Schrijvers et al., 2011) and cancer (Ozpolat and Benbrook, 2015). Likewise, currently the

• Overall the expression of both components ligand and recepto

  2023-03-21

  

  Overall, the expression of both components (ligand and receptor) of the apelin signaling system allows for analysis of the direct role of apelin in CL function, and specifically P4 production. Although the CL secretes many different hormones, P4 is of predominant importance because it is necessary f

13160 records 305/878 page Previous Next First page 上5页 301302303304305 下5页 Last page